Assume = suppose to be the case WITHOUT PROOF
- We can’t assume the suspects to be guilty.
- I’m assuming everyone here has a pen to write with.
Presume = suppose something is the case on the BASIS OF PROBABILITY.
- I presume they are not coming since they haven’t replied to the invitation.
- I presume he is Dr Rajiv Zachariah, the cardiologist because there’s a stethoscope hanging around his neck.