housekeeper = A person, esp. a woman whose job is to organise another person’s house and deal with cooking, cleaning, etc.

• We can’t afford to employ a housekeeper.
• After his wife’s death he decided to employ a housekeeper.

housewife = A married woman who does not have a full-time job outside the house.

• Indira doesn’t want to give up her job and become a housewife.
• Most women in Kerala don’t necessarily give up their jobs and become housewives when they get married.